Antiviral activity of a Rac GEF inhibitor characterized with a sensitive HIV/SIV fusion assay.
نویسندگان
چکیده
A virus-dependent fusion assay was utilized to examine the activity of a panel of HIV-1, -2, and SIV isolates of distinct coreceptor phenotypes. This assay allowed identification of entry inhibitors, and characterization of an antagonist of a Rac guanine nucleotide exchange factor, as an inhibitor of HIV-mediated fusion.
منابع مشابه
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عنوان ژورنال:
- Virology
دوره 368 1 شماره
صفحات -
تاریخ انتشار 2007